No prolongar más de 24 horas la profilaxis antibiótica después de una intervención quirúrgica no complicada.
Williams DM, Gustilo RB. The use of preventive antibiotics in orthopaedic surgery. Clin Orthop Relat Res 1984;190:83-8
Mauerhan y cols. Prophylaxis against infection in total joint arthroplasty. One day of cefuroxime compared with three days of cefazolin. J Bone Joint Surg 1994;76:39-45.
Gillespie WJ, Walenkamp JH. Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures. Cochrane Database Syst Rev 2010;17(3):CD000244.